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. 2015 Oct 13;11:64. doi: 10.1186/s12990-015-0067-5

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© Betelli et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Different effects of muscimol on synapses exhibiting control PPRs that are less than or greater than 0.43. a Percentage changes of the first and second eEPSC peak, represented, for each individual neuron, as a function of PPR_ctl. The first peak is always depressed (left), while the second peak is mainly increased in synapses with PPR_ctl <0.43 (n = 6) and mainly depressed in synapses having PPR_ctl >0.43 (n = 8) (right). The regression line is represented for both samples of data. b Average values of percentage peak changes obtained from the data shown in a. c Muscimol causes a significant increase of PPR in both synapse populations (PPR_ctl <0.43: paired t test, p = 0.009, n = 6; PPR_ctl >0.43: paired t test, p = 0.003, n = 8)