TABLE 3—
Intervention Effect for the Secondary Outcome Variables by Study Group
| Intervention Group (n = 154/182) |
Control Group (n = 179/191) |
Intervention Effect (Adjusted Model)a |
||||||||
| Secondary Outcomes | Base | Exitb | ∆, 95% CI | P | Base | Exit | ∆, 95% CI | P | Coefficient (95% CI) | P |
| Symptom nights per 2 wk | ||||||||||
| Completers only | 3.19 | 1.08 | −2.11 (−2.76, −1.46) | < .001 | 2.85 | 2.12 | −0.74 (−1.28, −0.19) | .009 | −1.09 (−1.70, −0.48) | < .001 |
| Multiple imputation | 3.24 | 1.17 | −2.07 (−2.47, −1.67) | < .001 | 2.99 | 2.14 | −0.86 (−1.25, −0.46) | < .001 | −0.97 (−1.59, −0.35) | .002 |
| Activity limitation days per 2 wk | ||||||||||
| Completers only | 4.16 | 1.23 | −2.93 (−3.70, −2.16) | < .001 | 3.39 | 1.80 | −1.59 (−2.21, −0.97) | < .001 | −0.64 (−1.27, −0.02) | .044 |
| Multiple imputation | 4.09 | 1.21 | −2.89 (−3.43, −2.35) | < .001 | 3.47 | 1.81 | −1.66 (−2.14, −1.19) | < .001 | −0.63 (−1.25, −0.06) | .048 |
| Rescue medication use days per 2 wk | ||||||||||
| Completers only | 5.83 | 2.18 | −3.65 (−4.64, −2.65) | < .001 | 4.78 | 3.73 | −1.05 (−1.83, −0.27) | .008 | −1.70 (−2.59, −0.81) | < .001 |
| Multiple imputation | 5.67 | 2.31 | −3.36 (3.99, −2.74) | < .001 | 4.96 | 3.73 | −1.26 (−1.84, −0.68) | < .001 | −1.48 (−2.36, −0.60) | .001 |
| Asthma episodes per 3 mo | ||||||||||
| Completers only | 5.00 | 2.50 | −2.50 (−4.71, −0.29) | .027 | 3.96 | 3.50 | −0.46 (−1.73, 0.80) | .471 | −0.99 (−2.67, 0.68) | .244 |
| Multiple imputation | 4.88 | 2.58 | −2.31 (−3.81, −0.81) | .003 | 4.55 | 3.50 | −1.06 (−2.28, 0.16) | .089 | −0.84 (−2.41, 0.73) | .293 |
| Well-controlled asthma (%) | ||||||||||
| Completers only | 3.25 | 48.05 | 44.81 (36.10, 53.51) | < .001 | 6.70 | 22.91 | 16.20 (8.87, 23.54) | < .001 | 3.33c (2.05, 5.40) | < .001 |
| Multiple imputation | 3.30 | 46.03 | 42.74 (40.54, 44.94) | < .001 | 6.28 | 23.47 | 17.19 (14.57, 19.81) | < .001 | 2.90c (1.78, 4.73) | < .001 |
| Very poorly controlled (%) | ||||||||||
| Completers only | 50.00 | 17.53 | −32.47 (−42.96, −21.98) | < .001 | 45.25 | 24.02 | −21.23 (−30.26, −12.19) | < .001 | 0.65c (0.37, 1.14) | .135 |
| Multiple imputation | 49.45 | 17.90 | −31.55 (−38.20, −24.91) | < .001 | 46.60 | 23.94 | −22.66 (−29.03, −16.30) | < .001 | 0.69c (0.39, 1.21) | .194 |
Note. CI = confidence interval.
a
Regression-adjusted before and after differences between intervention and control groups controlling for age, gender, race/ethnicity (as White, Black, Hispanic, and Other), and education level.
b
Time at which study completion data were collected (approximately 1 year after baseline).
c
Odds ratios from a logistic regression model controlling for the same covariates.