Table 1.
Patient demographics
| Characteristic | No. of patients n = 43, n (%) |
|---|---|
| Patients | 43 (100) |
| Age at presentation (y) | |
| < 5 y | 39 (90.7) |
| ≥ 5 y | 4 (9.3) |
| Gender | |
| Male | 18 (41.9) |
| Female | 25 (58.1) |
| Hereditary pattern | |
| Sporadic | 42 (97.7) |
| Familial | 1 (2.3) |
| Laterality | |
| Unilateral | 34 (79.1) |
| Bilateral | 9 (20.9) |
| Unilateral (n = 34) | |
| Right | 21 (61.8) |
| Left | 13 (38.2) |
| First clinical presenting signs | |
| Leucocoria | 34 (79.1) |
| Strabismus | 5 (11.6) |
| Proptosis | 3 (7.0) |
| Swelling | 1 (2.3) |
| cTNM clinical classification | |
| T classification | |
| T1 | 10 (23.3) |
| T2 | 14 (32.6) |
| T3 | 11 (25.6) |
| T4 | 8 (18.6) |
| N classification | |
| N0 | 20 (46.5) |
| N1 | 17 (39.5) |
| N2 | 6 (14.0) |
| M classification | |
| M0 | 31 (72.1) |
| M1 | 12 (27.9) |
| cTNM stage | |
| I | 2 (4.7) |
| II | 12 (27.9) |
| III | 17 (39.5) |
| IV | 12 (27.9) |
| Largest tumor base (mm), mean (median, range) | 11.3 (5–26) |
| ≤ 15 mm | 28 (58.1) |
| > 15 mm | 15 (41.9) |
| Tumor thickness (mm), mean (median, range) | 8.6 (9, 3–16) |
| ≤ 10 mm | 25 (58.1) |
| > 10 mm | 18 (41.9) |
| Growth pattern | |
| Endophytic | 12 (27.9) |
| Exophytic | 20 (46.5) |
| Mixed | 5 (11.6) |
| Diffuse infiltrating | 6 (14.0) |
| Differentiation | |
| Well | 9 (20.9) |
| Moderate | 15 (34.9) |
| Poorly | 19 (44.2) |
| Treatment | |
| Eye enucleated | 19 (44.2) |
| Enucleated + chemotherapy | 22 (51.2) |
| Enucleated + chemotherapy + radiation therapy | 2 (4.7) |
| Outcomes | |
| Death | 14 (32.6) |
| Survival | 29 (67.4) |