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The time-dependent in vivo fluorescence images of DiR solution and DiR-loaded micelles in A549 tumor-bearing female nude mice after tail vein injection (A). The location of tumors is illustrated by black arrows. In vitro fluorescence images of excised organs and tumor tissues of nude mice at 8 h after injection of DiR solution and DiR-loaded micelle formulations (B).
Abbreviations: h, hours; min, minutes; DiR, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindotricarbocyanine iodide.
