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ORC binding sites are nucleosome depleted in S2 cells and ovarian follicle cells. Average nucleosome occupancy at ORC sites genome wide (y-axis) is plotted around the center of the ORC binding sites (x-axis) for follicle cells at different stages (OR_s8.1, OR_s8.2, OR_10.1, OR_10.2, dap_s10, OR_s12.1) and S2 cells in culture (S2cell.1, S2cell.2, S2cell.3). ORC sites with binding score >7.5 and S2 cell MNase-Seq data were from published sources (36,79).
