Table 1.
Baseline characteristics of included patients, based on transfusion status
| Characteristic | Overall (n = 17 523) | Transfused (n = 4672) | Not transfused (n = 12 851) | P-value | |
|---|---|---|---|---|---|
| Age (years old) | <40 | 982 (5.6) | 184 (3.9) | 798 (6.2) | <0.0001 |
| 40–64 | 7826 (44.7) | 1904 (40.8) | 5922 (46.1) | ||
| 65–74 | 5137 (29.3) | 1432 (30.7) | 3705 (28.8) | ||
| ≥75 | 3578 (20.4) | 1152 (24.7) | 2426 (18.9) | ||
| Male gender | 8566 (48.9) | 2318 (49.6) | 6248 (48.6) | 0.2435 | |
| Race | White | 11 919 (68.0) | 3010 (64.4) | 8909 (69.3) | <0.0001 |
| Black | 1463 (8.4) | 450 (9.6) | 1013 (7.9) | ||
| Other | 515 (2.9) | 161 (3.5) | 354 (2.8) | ||
| Unknown | 3626 (20.7) | 1051 (22.5) | 2575 (20.0) | ||
| ASA Score | I | 187 (1.1) | 22 (0.5) | 165 (1.3) | <0.0001 |
| II | 5075 (29.0) | 906 (19.4) | 4169 (32.4) | ||
| III | 11 387 (65.0) | 3357 (71.9) | 8030 (62.5) | ||
| IV/V | 874 (5.0) | 387 (8.3) | 487 (3.8) | ||
| BMI | <20 | 1139 (6.5) | 357 (7.6) | 782 (6.1) | <0.0001 |
| 20–29 | 11 288 (64.4) | 2984 (63.9) | 8304 (64.6) | ||
| 30–40 | 4260 (24.3) | 1107 (23.7) | 3153 (24.5) | ||
| ≥40 | 727 (4.2) | 180 (3.9) | 547 (4.3) | ||
| Unknown | 109 (0.62) | 44 (0.94) | 65 (0.51) | ||
| Malignant diagnosis | 11 484 (65.5) | 3466 (74.2) | 8018 (62.4) | <0.0001 | |
| Diabetes | 2949 (16.8) | 1069 (22.9) | 1880 (14.6) | <0.0001 | |
| Active smoker | 3693 (21.1) | 915 (19.6) | 2778 (21.6) | 0.0037 | |
| COPD | 816 (4.7) | 257 (5.5) | 559 (4.4) | 0.0014 | |
| Dyspnea | At rest | 88 (0.5) | 41 (0.9) | 47 (0.4) | <0.0001 |
| With moderate exertion | 1398 (8.0) | 438 (9.4) | 960 (7.5) | ||
| Cardio-vascular comorbidity | 10 721 (61.2) | 3122 (66.8) | 7599 (59.1) | <0.0001 | |
| Bleeding disorder | 506 (2.9) | 207 (4.4) | 299 (2.3) | <0.0001 | |
| Corticosteroid use | 375 (2.1) | 145 (3.1) | 230 (1.8) | <0.0001 | |
| Weight loss > 10% | 2619 (15.0) | 885 (18.9) | 1734 (13.5) | <0.0001 | |
| Pre-operative haematocrit (%) | 37.9 (34.8–41.4) | 35.2 (31.5–39.0) | 38.9 (36.0–42.0) | <0.0001 | |
Values are n (%) or mean [interquartile range (IQR)].
*
15 481 data missing for serum albumin, 15 584 for serum bilirubin and 14 989 for INR.
ASA, American Society of Anesthesiologists; BMI, body mass index; COPD, chronic obstructive pulmonary disease; INR, International Normalized Ratio.