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. 2015 Sep 3;17(11):988–993. doi: 10.1111/hpb.12479

Table 2.

Histopathological data for patients with, respectively, giant (G-HCC) and small (S-HCC) hepatocellular carcinoma

S-HCC n (%) G-HCC n (%) P-value
Patients, n 63 23
Gross vascular invasion
(n = 62) (n = 23)
 Yes 4 (6.5%) 0 0.570
 No 58 (93.5%) 23 (100%)
Microvascular invasion
(n = 62) (n = 23)
 Yes 13 (21.0%) 11 (47.8%) 0.028
 No 49 (79.0%) 12 (52.2%)
Perineural invasion
(n = 62) (n = 23)
 Yes 2 (3.2%) 0 1.000
 No 60 (96.8%) 23 (100%)
Lymphoinvasion
(n = 62) (n = 23)
 Yes 11 (17.7%) 9 (39.1%) 0.048
 No 51 (82.3%) 14 (60.9%)
Presence of tumour capsule
(n = 63) (n = 23)
 Yes 37 (58.7%) 18 (78.3%) 0.129
 No 26 (41.3%) 5 (21.7%)
Tumour capsule invasion
(n = 36) (n = 18)
 Yes 11 (30.6%) 3 (16.7%) 0.339
 No 25 (69.4%) 15 (83.3%)
Presence of satellite lesions
(n = 62) (n = 23)
 Yes 12 (19.4%) 5 (21.7%) 0.770
 No 50 (80.6%) 18 (78.3%)
Presence of tumour rupture
(n = 61) (n = 23)
 Yes 6 (9.8%) 2 (8.7%) 1.00
 No 55 (90.2%) 21 (91.3%)
Margins involved
(n = 61) (n = 23)
 Yes 1 (1.6%) 3 (13.0%) 0.061
 No 60 (98.4%) 20 (87.0%)
Presence of liver cirrhosis
(n = 63) (n = 23)
 Yes 32 (50.8%) 3 (13.0%) 0.002
 No 31 (49.2%) 20 (87.0%)

P-values in bold indicate differences of statistical significance at < 0.05.