FIG. 4.

Levels of major costimulatory molecules remained unchanged in hESCs with diminished B2M expression in either undifferentiated or fully differentiated states. Gene expression levels of major costimulatory molecules, including CD80, CD81, CD83, CD86, FAS, and FAS-Ligand, after normalization to housekeeping gene TBP (human TATA box binding protein). No significant differences between G-Par and G-Mod cells were found in either undifferentiated (day 1) or fully differentiated (day 21) states.