Skip to main content
. 2015 Sep 17;21(19-20):2572–2582. doi: 10.1089/ten.tea.2014.0504

FIG. 3.

FIG. 3.

GSCs exhibit elongated single-cell movement in collagen-I, BD1.5 (BD collagen 1.5 mg/mL), Oli (oligomer), and Ate (atelocollagen). (A) GSC neurospheres embedded in multiple types of collagen type-I matrices present a single migration mode. Scale bars 100 μm. (B) Cells cultured in acid-solubilized matrices of low collagen concentration (BD-1.5 and Oli-1.5, Oli-2 mg/mL) presented the highest distance of migration. (C) Maximum velocity was reached during the first 24 h of culture and decreased subsequently. Similar to B, the highest velocity was reached in BD-1.5 mg/mL and Oli-1.5, 2 mg/mL. Values marked as * are statistically different from **p-value < 0.05, † are statistically different from ††p-value < 0.05. n = 9 (oligomer), n > 4 (BD collagen and atelocollagen), error bars indicate ± SEM.