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. 2015 Sep 17;21(19-20):2572–2582. doi: 10.1089/ten.tea.2014.0504

FIG. 5.

FIG. 5.

(A) GSCs present single-cell migration in composite oligomer–hyaluronan (HA) matrices similar to only oligomer matrices. Increasing concentration of HA decreases the number of migrating cells and alters the morphology of the migratory cells from elongated to spherical shaped. White arrowheads point out elongated migrating cells and black arrowheads point out rounded migrating cells. Scale bars 100 μm. (B) Distance of migration is reduced with increasing presence of HA. All matrices present statistically different distance at all time points, except HA:2-Col:2 and HA:5-Col:2 mg/mL. (C) Velocity decreased with time as observed with other matrix types, except HA:10-Col:2 mg/mL matrix where the velocity increased with time. Values marked as * are statistically different from **, ** are statistically different from *** p-value < 0.05, † are statistically different from †† p-value < 0.05, #, ##, and ### are statistically different, p-value < 0.05. n = 9, error bars indicate ± SEM.