Table 5. Patients characteristic of malignant transformed and untransformed cases in PMOLS.
Patients Characteristics | Untransformed PMOLs (N = 62) | Malignant transformed PMOLs (N = 10) | P-value |
---|---|---|---|
Age (Years) | |||
Mean ± SD | 37.81± 11.98 | 43.60± 18.65 | 0.383 |
Range | 20–80 | 22–75 | |
Sex N (%) | |||
Female | 17 (27.42%) | 1 (10%) | 0.238 |
Male | 45 (72.58%) | 9 (90%) | |
Dysplasia | |||
Present | 41 (66.13%) | 10 (100%) | 0.029 |
Mild | 7 | 0 | |
Moderate | 15 | 0 | |
Severe | 19 | 10 | |
Absent | 21 (33.87%) | 0 (0%) | |
Tobacco chewing habit | |||
Present | 40 (64.52%) | 8 (80%) | 0.335 |
Absent | 22 (35.48%) | 2 (20%) | |
Alcohol | |||
Present | 24 (38.71%) | 4 (40%) | 0.938 |
Absent | 38 (61.29%) | 6 (60%) | |
Smoke | |||
Present | 29 (46.77%) | 7 (70%) | 0.173 |
Absent | 33 (53.23%) | 3 (30%) | |
Follow—up | |||
Mean | 26.21 | 29.41 | 0.749 |
Range(months) | 3–55 | 10–60 | |
FGF-2 expression | |||
Negative | 47 (75.81%) | 1 (10%) | 0.000 |
Positive | 15 (24.19%) | 9 (90%) | |
FGFR-2 expression | |||
Negative | 46 (74.19%) | 2 (20%) | 0.001 |
Positive | 16 (25.81%) | 8 (80%) | |
FGFR-3 expression | |||
Negative | 39 (62.90%) | 4 (40%) | 0.171 |
Positive | 23 (37.10%) | 6 (60%) |