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. 2015 Oct 14;10(10):e0138801. doi: 10.1371/journal.pone.0138801

Table 5. Patients characteristic of malignant transformed and untransformed cases in PMOLS.

Patients Characteristics Untransformed PMOLs (N = 62) Malignant transformed PMOLs (N = 10) P-value
Age (Years)
Mean ± SD 37.81± 11.98 43.60± 18.65 0.383
Range 20–80 22–75
Sex N (%)
Female 17 (27.42%) 1 (10%) 0.238
Male 45 (72.58%) 9 (90%)
Dysplasia
Present 41 (66.13%) 10 (100%) 0.029
Mild 7 0
Moderate 15 0
Severe 19 10
Absent 21 (33.87%) 0 (0%)
Tobacco chewing habit
Present 40 (64.52%) 8 (80%) 0.335
Absent 22 (35.48%) 2 (20%)
Alcohol
Present 24 (38.71%) 4 (40%) 0.938
Absent 38 (61.29%) 6 (60%)
Smoke
Present 29 (46.77%) 7 (70%) 0.173
Absent 33 (53.23%) 3 (30%)
Follow—up
Mean 26.21 29.41 0.749
Range(months) 3–55 10–60
FGF-2 expression
Negative 47 (75.81%) 1 (10%) 0.000
Positive 15 (24.19%) 9 (90%)
FGFR-2 expression
Negative 46 (74.19%) 2 (20%) 0.001
Positive 16 (25.81%) 8 (80%)
FGFR-3 expression
Negative 39 (62.90%) 4 (40%) 0.171
Positive 23 (37.10%) 6 (60%)