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. 2015 Oct 14;10(10):e0140450. doi: 10.1371/journal.pone.0140450

Table 3. Rate ratio (RR) of recurrent subdural haematoma (SDH) in surgically- and conservatively treated patients, according to potential predictors in Denmark 1996–2011.

Potential predictors for recurrent SDH Surgical treatment Conservative treatment P-value +
Events Adjusted RR ** (95% CI*) Events Adjusted RR ** (95% CI*)
Age (years)
 20–49 123 1 (Ref.) 132 1 (Ref.) 0.005
 50–69 317 0.90 (0.73–1.12) 194 1.29 (1.04–1.62)
 70- 517 1.12 (0.91–1.38) 272 1.79 (1.44–2.23)
Gender
 Males 743 1.69 (1.45–1.97) 414 1.50 (1.26–1.79) 0.31
 Females 214 1 (Ref.) 184 1 (Ref.)
Alcohol addiction
 Yes 186 1.29 (1.08–1.53) 150 1.10 (0.90–1.33) 0.20
 No 771 1 (Ref.) 448 1 (Ref.)
Chronic liver disease
 Yes 43 1.35 (0.96–1.83) 32 1.19 (0.81–1.68) 0.60
 No 914 1 (Ref.) 566 1 (Ref.)
Coagulopathy
 Yes 6 0.70 (0.28–1.42) 9 2.24 (1.07–4.10) 0.03
 No 951 1 (Ref.) 589 1 (Ref.)
Renal insufficiency
 Yes 18 0.92 (0.56–1.43) 18 1.65 (0.99–2.56) 0.09
 No 939 1 (Ref.) 580 1 (Ref.)
Diabetes mellitus
 Yes 53 1.24 (0.92–1.64) 40 1.67 (1.18–2.29) 0.18
 No 904 1 (Ref.) 558 1 (Ref.)
Previous cerebral ischemic infarction
 Yes 60 0.86 (0.66–1.11) 53 1.25 (0.93–1.64) 0.07
 No 897 1 (Ref.) 545 1 (Ref.)
Statins
 Yes 112 1.00 (0.81–1.24) 60 0.93 (0.69–1.22) 0.64
 No 845 1 (Ref.) 538 1 (Ref.)
Trauma diagnosis
 Yes 531 1.19 (1.04–1.36) 396 1.06 (0.89–1.26) 0.30
 No 426 1 (Ref.) 202 1 (Ref.)
PDMD ††
 Yes 17 1.11 (0.66–1.74) 13 0.98 (0.53–1.63) 0.74
 No 940 1 (Ref.) 585 1 (Ref.)

* 95% Confidence interval

** Rate ratios adjusted for age, gender, calendar period, time since admittance for first SDH, length of hospital stay for the primary SDH, and the potential predictors for recurrent SDH listed in Table 1.

+ P-value: test for similar RR’s for surgically vs conservatively treated patients for each predictive factor.

Trauma diagnosis less than 2 years before the primary SDH

†† PDMD: Pre-packaged Daily Medication Doses.