Table 3. Multivariate mixed effects linear regression of log-miR-17, as obtained by image analysis, in normal, adenomatous and invasive tissue of the colon.
| N | Log-miR-17 | P value | ||
|---|---|---|---|---|
| Coefficient (SE) | ||||
| Variable | ||||
| Tissue type | ||||
| Normal | 16 | ref. | ||
| Low grade adenoma | 5 | 0.88 (0.41) | 0.03 | |
| High grade adenoma | 13 | 2.23 (0.28) | <0.001 | |
| Adenocarcinoma | 16 | 2.30 (0.27) | <0.001 | |
| Adenoma histology | ||||
| Tubular | 16 | ref. | ||
| Tubulovillous | 16 | -0.01 (0.34) | 0.98 | |
| Villous | 16 | 0.78 (0.65) | 0.23 | |
| Gender specific age | ||||
| Female | 5 | -0.003 (0.03) | 0.91 | |
| Male | 11 | 0.09 (0.02) | <0.001 | |