Table 2. Simple linear regression analysis using muscle mass (SMM or ASM) as dependent variable in 111 HD subjects 1 .
SMM | ASM | |||||||
---|---|---|---|---|---|---|---|---|
β | 95% CI | R2 | P value | β | 95% CI | R2 | P value | |
Univariate significant | ||||||||
n-3 PUFA intake, g/day | 1.160 | 0.396 to 1.924 | 0.077 | 0.003 | 1.043 | 0.419 to 1.667 | 0.091 | 0.001 |
Ratio of n-6/n-3 PUFA, g/day | -0.161 | -0.315 to -0.007 | 0.038 | 0.041 | -0.162 | -0.287 to -0.036 | 0.057 | 0.012 |
BMI, kg/m2 | 0.721 | 0.467 to 0.976 | 0.225 | < .0001 | 0.576 | 0.365 to 0.788 | 0.211 | < .0001 |
Creatinine, mg/dL | 1.257 | 0.797 to 1.717 | 0.212 | < .0001 | 1.011 | 0.629 to 1.393 | 0.201 | < .0001 |
eKt/V | -11.014 | -13.561 to -8.468 | 0.402 | < .0001 | -9.052 | -11.155 to -6.949 | 0.395 | < .0001 |
Nonsignificant relevant covariates | ||||||||
Dialysis vintage, year | -0.183 | -0.377 to 0.012 | 0.031 | 0.066 | -0.155 | -0.315 to 0.006 | 0.032 | 0.059 |
HOMA-IR | 0.124 | -0.075 to 0.323 | 0.014 | 0.220 | 0.104 | -0.060 to 0.268 | 0.014 | 0.213 |
hs CRP, mg/dL | 1.092 | -0.236 to 2.420 | 0.023 | 0.106 | 1.080 | -0.009 to 2.169 | 0.034 | 0.052 |
Abbreviations: SMM, skeletal muscle mass; ASM, appendicular skeletal muscle mass; HD, hemodialysis; BMI, body mass index; PUFA, polyunsaturated fatty acid; eKt/V: equilibrated Kt/V; HOMA-IR, homoeostasis model assessment-estimated insulin resistance; hs CRP, high-sensitivity C reactive protein; CI, confidence interval
1β refers to the regression coefficient that demonstrated the change in muscle mass per kg change in the exposure variable