Table 1. Clinical features in primary and recurrent glioblastoma patients.
Features | Total patients (n = 28) |
---|---|
Age (years) | 51.18 ± 14.20 |
Median | 50.5 (24~77) |
<50 | 14/28 (50%) |
51–60 | 5/28 (18%) |
61–70 | 6/28 (21%) |
>70 | 3/28 (11%) |
Gender | |
Male: Female | 14:14 |
Hospital management | |
AJOU/KU/CNU/SNU | 9/6/8/5 |
Tumor Volume (cm3) | 45.65 ± 21.35 |
Median | 46.20 (19.6 ~116.4) |
MR necrosis (%) | |
No necrosis | 2/28 (7%) |
<25% | 8/28 (29%) |
25–50% | 4/28 (14%) |
>50% | 14/28 (50%) |
Ependymal involvement | |
YES | 10/28 (36%) |
NO | 18/28 (64%) |
Initial KPS | |
90–100 | 15/28 (53%) |
70–80 | 11/28 (40%) |
<70 | 2/28 (7%) |
Included glioblastoma tissue in this study | |
Primary glioblastoma only | 10/28 (32%) |
Recurred glioblastoma only | 3/28 (11%) |
Both primary and recurred glioblastoma | 15/28 (54%) |
Initial resection | |
Gross total resection | 17/28 (60%) |
Subtotal resection (50 ~90%) | 8/28 (29%) |
Partial resection (<50%) | 3/28 (11%) |
Progression free survival (months) | 14.91 ± 12.17 |
Median | 10.75 (5~62.4) |
Overall Survival (months) | 26.16 ± 18.20 |
Median | 20 (9~ 78) |
AJOU: Ajou University Hospital, KU: Korea University Hospital, CNU: Chonnam National University Hospital, SNU: Seoul National University Hospital, MR: magnetic resonance; KPS: Karnofsky Performance Status Scale.