Table 7. Median (range) and p-values for the transcription of target genes within skin samples.
| Genes (Skin) | Controls | Group 1 (6 months post infection) | Group 2 (15 months post infection) | Controls vs Group 1 | Controls vs Group 2 | Group 1 vs Group 2 |
|---|---|---|---|---|---|---|
| TLR2 | 67.93 (35.42–100.44) | 201.43 (107.29–316.82) | 130.71 (129.19–198.86) | p = 0.042 | p = 0.171 | p = 0.462 |
| TLR3 | 277.62 (155.65–399.59) | 351.49(99.57–802.59) | 125.43 (60.34–125.60) | p = 0.728 | p = 0.257 | p = 0.038 |
| TLR4 | 157.39 (120.51–194.28) | 172.54 (118.81–267.37) | 103.71 (102.90–323.95) | p = 0.262 | p = 0.762 | p = 0.940 |
| TLR9 | 307.64 (214.71–400.57) | 1152.08 (509.62–1625.92) | 174.57 (73.13–229.63) | p = 0.007* | p = 1.000 | p = 0.044 |
| IL-17 | 0.43 (0.23–0.64) | 0.98 (0.31–9.06) | 2.70 (0.98–4.12) | p = 0.218 | p = 0.200 | p = 0.282 |
| IL-22 | 9.57(2.15–16.99) | 5.01 (1.91–9.02) | 2.51 (0.28–5.92) | p = 0.924 | p = 0.171 | p = 0.093 |
| FoxP3 | 1.07 (0.82–1.33) | 11.06 (1.53–21.54) | 6.50 (1.73–8.93) | p = 0.019^ | p = 0.019^ | p = 0.550 |
Significant Bonferroni corrected p-values are highlighted bold (p< = α/3).
(*)p-value<0.016.
(^) indicates marginal significance.