Table 5. Complications and Infections.
Intent-to-treat | On-treatment | ||||
---|---|---|---|---|---|
Complications | CNI Minimized | CNI Withdrawn | p-value | CNI Withdrawn | p-value |
n = | 88 | 90 | 65 | ||
rATG reaction | 3 (3.4%) | 6 (6.7%) | 0.5 | 2 (5%) | 0.70 |
ATN/DGF | 4 (4.5%) | 8 (8.9%) | 0.37 | 6 (9%) | 0.32 |
Myocardial infarction | 1 (1.1%) | 2 (2.2%) | 1.0 | 1 (2%) | 1.0 |
Cardiac arrhythmia | 0 (0%) | 2 (2.2%) | 0.50 | 2 (3%) | 0.18 |
Serum sickness | 1 (1.1%) | 2 (2.2%) | 1.0 | 2 (3%) | 0.57 |
Lymphocele requiring drainage | 4 (4.5%) | 6 (6.7%) | 0.75 | 5 (8%) | 0.50 |
Wound complications | 2 (2.3%) | 3 (3.3%) | 1.0 | 2 (3%) | 1.0 |
Transplant wound hernia requiring repair | 7 (8.0%) | 13 (14.4%) | 0.24 | 11 (17%) | 0.12 |
Ureteral obstruction | 5 (5.7%) | 2 (2.2%) | 0.28 | 0 (0%) | 0.07 |
Cancer | 4 (4.5%) | 5 (5.6%) | 1.0 | 3 (5%) | 1.0 |
Infections | CNI Minimized | CNI Withdrawn | p-value | CNI Withdrawn | p-value |
n = | 88 | 90 | – | 64 | – |
Urinary tract infection | 17 | 18 | 1.0 | 13 | 1.0 |
Bacterial pneumonia | 5 | 3 | 0.50 | 1 | 0.40 |
Bacteremia | 7 | 5 | 0.56 | 4 | 0.76 |
Fungal | 1 | 2 | 1.0 | 1 | 1.0 |
CMV infection (disease, viremia, syndrome) | 3 | 6 | 0.50 | 3 | 0.70 |
BK nephropathy | 3 | 3 | 1.0 | 1 | 0.64 |
PTLD | 3 | 0 | 0.12 | 0 | 0.26 |
Total infections | 39 | 37 | 0.76 | 23 | 0.32 |