Skip to main content
. 2015 Oct 14;10(10):e0138623. doi: 10.1371/journal.pone.0138623

Fig 1. Level of hCD45+ Cell Engraftment in the BM and Fold Increase in Engraftment Observed in NSG Mice Transplanted with CBSC and CB NK Cells.

Fig 1

(A) CD69 expression measured as mean fluorescence intensity (MFI) on CB NK cells before and after incubation with 20 ng/mL IL-15 for 4 h (N = 18). (B) Percentage of hCD45+ cells detected by flow cytometry in the BM of NSG mice ten weeks post-transplant with CBSC alone or in combination with CD4+ T cells, CD8+ T cells, rNK cells or aNK cells (N = 4). (C) Percentage of hCD45+ cells detected by flow cytometry in the BM of NSG mice ten weeks post-transplant with CBSC alone or in combination with rNK cells or aNK cells (N = 14). (D) Percentage of hCD45+ cells detected by flow cytometry in the BM of NSG mice transplanted with CBSC alone or in combination with rNK cells or aNK cells from 6 different CB units (N = 18). * P < 0.05, ** P < 0.01, *** P < 0.001.