Table 2.

Patient demographics and baseline characteristics and association with hospital length of stay (LOS) and 30-day readmission in 39,324 hospital admissions for sickle cell crisis among 4,348 adult patients.

	Number of admissions	Mean (95% range) LOS in days	Number of non-fatal admissions	Rate (95% CI) of 30- day readmission
Overall	39,324	5.9 (1.0–19.0)	39,136	39.6%
Baseline characteristics
Age
≤ median of 28 years	21,086	5.6 (1.0–18.0)	21,009	41.5% (40.8%–42.1%)
> median of 28 years	18,238	6.1 (1.0–21.0)	18,127	37.4% (36.7%–38.1%)
Male	15,486	5.6 (1.0–18.0)	15,389	38.9% (38.1%–40.0%)
Female	23,838	6.0 (1.0–20.0)	23,747	39.9% (39.4%–40.6%)
Opioid treatment1	28,465	5.8 (1.0–19.0)	28,360	45.7% (45.1%–46.3%)
Hydroxyurea1	11,299	5.7 (1.0–18.0)	11,262	48.8% (47.8%–50.0%)
NSAID treatment1	11,050	5.4 (1.0–17.0)	11,011	42.3% (41.4%–43.2%)
Steroid treatment1	2,284	5.8 (1.0–19.0)	2,276	48.0% (45.9%–50.0%)
Cardiopulmonary disease	10,030	6.2 (1.0–20.0)	9,972	42.9% (41.9%–43.9%)
Chronic Asthma	5,534	5.4 (1.0–16.0)	5,524	47.0% (45.7%–48.3%)
Chronic renal disease	1,733	7.2 (1.0–29.7)	1,691	35.3% (33.0%–37.6%)
Chronic liver disease	1,155	7.4 (1.0–23.1)	1,143	43.7% (40.9%–46.6%)
Iron overload	1,073	7.0 (2.0–22.0)	1,073	45.2% (42.2%–48.2%)
Acute comorbidities
Acute chest syndrome or pneumonia	6,767	7.8 (1.0–26.0)	6,644	32.5% (31.4%–33.6%)
Sepsis	2,044	11.0 (1.0–38.0)	1,969	44.4% (42.2%–46.6%)
Acute renal failure	1,447	9.0 (1.0–33.8)	1,374	34.6% (32.1%–37.1%)
Acute multi-organ failure	527	12.0 (1.0–44.6)	464	30.8% (26.6%–35.0%)
Acute stroke	335	9.2 (1.0–36.6)	319	35.4% (30.1%–40.7%)
Acute liver failure	104	11.9 (1.0–54.3)	85	30.6% (20.6%–40.6%)
Hospital course
LOS, days
1–3	14,329	NA	14,238	37.1% (36.3%–37.9%)
4+	24,995		24,898	41.0% (40.4%–41.6%)

¹From outpatient claims