Table 6.
Hospital length of stay (LOS) and 30-day readmission rate by red blood cell transfusion status in subpopulations of sickle cell crisis admissions.
| Subpopulation | Hospital LOS | 30-Day Readmissions | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Without simple red or exchange blood transfusion* | With simple red blood transfusion* | P value | Without simple red or exchange blood transfusion* | With simple red blood transfusion* | P value | |||||
| N | Days (95%CI) | N | Days (95%CI) | N | Rate | N | Rate | |||
| Overall | 26334 | 5.4 (5.3–5.5) | 12746 | 6.7 (6.6–6.8) | <0.001 | 26215 | 42.6% | 12683 | 33.3% | <0.001 |
| Baseline characteristics | ||||||||||
| Cardiopulmonary | 6808 | 5.8 (6.5–5.9) | 3143 | 7.1 (6.9–7.3) | <0.001 | 6768 | 47.0% | 3126 | 33.9% | <0.001 |
| disease | ||||||||||
| Asthma | 4136 | 5.0 (4.9–5.2) | 1362 | 6.5 (6.2–6.7) | <0.001 | 4127 | 50.2% | 1361 | 37.3% | <0.001 |
| Chronic renal disease | 872 | 7.7 (7.0–8.4) | 849 | 6.7 (8.3–7.2) | 0.028 | 847 | 39.0% | 833 | 32.1% | 0.004 |
| Chronic liver disease | 742 | 6.8 (6.4–7.3) | 403 | 8.2 (7.4–9.0) | 0.001 | 733 | 46.0% | 401 | 40.2% | 0.4 |
| Iron overload disorders | 532 | 6.6 (6.2–7.0) | 532 | 7.4 (6.9–7.9) | 0.013 | 532 | 50.4% | 532 | 40.2% | 0.015 |
| Acute comorbidities | ||||||||||
| Acute chest syndrome or pneumonia | 3862 | 7.4 (7.2–7.7) | 2763 | 8.2 (7.9–8.4) | <0.001 | 3788 | 35.5% | 2719 | 28.1% | <0.001 |
| Sepsis | 1164 | 11.0 (10.3–11.6) | 852 | 11.0 (10.4–11.7) | 0.8 | 1116 | 47.8% | 828 | 40.2% | 0.005 |
| Acute renal failure | 722 | 8.9 (8.2–9.6) | 694 | 8.9 (8.2–9.6) | 0.9 | 684 | 37.6% | 660 | 31.8% | 0.003 |
| Acute multi-organ failure | 252 | 12.3 (10.7–13.9) | 244 | 11.6 (10.2–13.0) | 0.5 | 218 | 32.6% | 215 | 30.2% | 0.3 |
| Acute Stroke | 201 | 8.2 (7.0–9.5) | 112 | 10.4 (8.7–12.0) | 0.040 | 192 | 38.0% | 105 | 30.5% | 0.3 |
| Acute liver failure | 50 | 11.4 (8.2–14.6) | 48 | 11.6 (7.0–16.1) | 0.9 | 43 | 30.2% | 36 | 33.3% | 0.7 |