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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Ann Otol Rhinol Laryngol. 2015 Jun 17;124(11):903–910. doi: 10.1177/0003489415591205

Figure 4. Axonal density traversing spiral lamina is decreased in the 60 Gy group.

Figure 4

(A) The auditory nerve fibers in the spiral lamina of a control mouse show minimal area unoccupied by bipolar axons or extracellular matrix. (B) The spiral lamina of a mouse 8 days post-irradiation with 60 Gy has areas devoid of axons, glia or extracellular matrix (arrows) at 8 days post-irradiation. Although the cells of the organ of Corti from spiral limbus to inner pillar cell appear normal, a vacuole (arrowhead) can be detected at the base of the inner hair cell. AN= auditory nerve fibers, SpL= spiral limbus, tm= tectorial membrane. Scale bar= 50 µm