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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Eur Urol. 2015 Aug 17;68(5):899–905. doi: 10.1016/j.eururo.2015.07.074

Table 3.

Multivariable Cox proportional hazards regression models predicting for urinary functional and erectile functional recovery

Predictor Urinary function
Erectile function
HR 95% CI p value HR 95% CI p value


Functional domain score at 12 mo 1.20 1.12–1.28 <0.0001 1.10 1.08–1.13 <0.0001
Patient age 0.96 0.94–0.99 0.002 0.98 0.96–1.00 0.045
Preoperative PSA 1.00 0.96–1.04 0.9 1.01 0.98–1.04 0.5
Body mass index 1.02 0.98–1.06 0.3 0.97 0.94–1.00 0.079
Comorbidities
 0 Ref. Ref.
 1 1.26 0.83–1.92 0.3 0.93 0.67–1.29 0.7
 2 0.94 0.59–1.49 0.8 0.71 0.46–1.10 0.12
 ≥3 1.13 0.63–2.03 0.7 1.19 0.71–2.02 0.5
Nerve-sparing status
 None Ref.
 Unilateral 0.98 0.53–1.83 1.0 1.91 0.74–4.96 0.2
 Bilateral 1.06 0.62–1.83 0.8 2.32 0.93–5.77 0.070
Pathologic Gleason score
 ≤6 Ref. Ref.
 7 1.19 0.77–1.83 0.4 1.27 0.87–1.86 0.2
 ≥8 1.22 0.55–2.74 0.6 1.23 0.57–2.68 0.6
Pathologic T stage
 T2 Ref. Ref.
 T3 or higher 0.91 0.64–1.30 0.6 1.05 0.75–1.46 0.8

CI = confidence interval; HR = hazard ratio; IIEF-6 = International Index of Erectile Function; PSA = prostate-specific antigen; Ref. = reference.

In patients who have urinary incontinence or erectile dysfunction at 12 mo after radical prostatectomy.

For erectile function, the modified IIEF-6 scoring was applied to the functional domain score at 12 mo.