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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Cytokine. 2015 Aug 5;76(2):244–252. doi: 10.1016/j.cyto.2015.07.027

Figure 2. Neutralization of IL-6 in B6.NOD-Aec mice leads to increased inflammation and apoptosis in SMG.

Figure 2

Anti-IL-6 or control IgG was injected to 16 week-old B6.NOD-Aec mice, 3 times weekly for 8 weeks. (A) H&E staining of SMG sections showing leukocytic foci. Original magnification: ×10. (B) In situ TUNEL staining of apoptotic cells in SMG sections. Original magnification: ×40. (C) Immunohistochemical staining of active caspase-3 in SMG sections. Data are representative of the analyses of 9 mice for each group from 5 independent experiments. Original magnification: ×40.