Figure 3. Neutralization of IL-6 in B6.NOD-Aec mice leads to increased IFN-γ and TNF-α expression in the SMG.
IFN-γ and TNF-α mRNA levels in the submandibular gland (SMG) and submandibular draining lymph nodes (SM LN) of B6.NOD-Aec mice injected with anti-IL-6 or control IgG as described in Figure 2. Expression levels were presented relative to that of β-actin. Data are the average of the analyses of 7 mice for each group from 4 independent experiments. The histograms and error bars represent the average and SEM, respectively.