Table 2.
Changes in hematologic parameters in the study groups.
| Parameters | Eprex | Pastopoitin | p-Value |
|---|---|---|---|
| Hb (g/dL) | |||
| Baseline | 8.48 ± 1.14 | 8.47 ± 0.94 | 0.11 |
| Endpoint | 9.81 ± 1.21a | 9.5 ± 1.25a | 0.25 |
| Hct (%) | |||
| Baseline | 27.41 ± 2.96 | 27.44 ± 2.86 | 0.64 |
| Endpoint | 31.82 ± 4.19a | 31.89 ± 3.11a | 0.06 |
| RBC (million/mm3) | |||
| Baseline | 3.12 ± 0.45 | 3.13 ± 0.38 | 0.38 |
| Endpoint | 3.77 ± 0.68a | 3.71 ± 0.43a | 0.17 |
| Platelet (1000/mL) | |||
| Baseline | 197.03 ± 88.28 | 203.86 ± 77.9 | 0.53 |
| Endpoint | 186.18 ± 66.63 | 228.33 ± 71.78 | 0.18 |
| MCV (fL) | |||
| Baseline | 87.3 ± 7.41 | 86.61 ± 7.71 | 0.3 |
| Endpoint | 86.16 ± 10.61 | 86.98 ± 7.23 | 0.65 |
| MCH (pg) | |||
| Baseline | 27.16 ± 3.01 | 26.72 ± 2.63 | 0.19 |
| Endpoint | 27.76 ± 10.35 | 26.04 ± 2.48 | 0.1 |
| MCHC (pg) | |||
| Baseline | 30.83 ± 2.06 | 30.81 ± 1.99 | 0.06 |
| Endpoint | 30.70 ± 2.11 | 29.98 ± 1.71 | 0.38 |
| WBC (103/mm3) | |||
| Baseline | 6.1 ± 2.45 | 6.52 ± 1.84 | 0.23 |
| Endpoint | 5.99 ± 1.55 | 6.81 ± 1.72 | 0.45 |
| RDW (%) | |||
| Baseline | 14.39 ± 2.18 | 14.4 ± 1.7 | 0.1 |
| Endpoint | 14.03 ± 1.88 | 14.46 ± 1.74 | 0.34 |
| Reticulocyte (%) | |||
| Baseline | 1.18 ± 0.46 | 1.35 ± 0.67 | 0.04 |
| Endpoint | 1.18 ± 0.55 | 1.32 ± 0.61 | 0.37 |
Significant difference versus baseline value (p < 0.05). Hb: hemoglobin; Hct: hematocrit; RBC: red blood cell; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; WBC: white blood cell; RDW: red blood cell distribution width.