Table 2.
Actual drug content, encapsulation efficiency and production yield.
| Batch code | Drug:Polymer ratio | Theoretical drug content (%) | Actual drug content (%) ± SDa | Encapsulation efficiency (%) ± SDa | Production yield (%) ± SDa |
|---|---|---|---|---|---|
| F1 | 1:1 | 50 | 47.78 ± 0.01 | 95.56 ± 0.02 | 24.55 ± 0.26 |
| F2 | 1:2 | 33.33 | 31.04 ± 0.03 | 93.12 ± 0.02 | 38.8 ± 0.23 |
| F3 | 1:3 | 25 | 22.49 ± 0.01 | 89.96 ± 0.06 | 42.6 ± 0.42 |
| F4 | 1:4 | 20 | 16.36 ± 0.17 | 81.8 ± 0.20 | 59.2 ± 0.01 |
| F5 | 1:5 | 16.63 | 12.61 ± 0.02 | 75.82 ± 0.03 | 71.13 ± 0.08 |
| F6 | 1:6 | 14.28 | 9.75 ± 0.01 | 68.22 ± 0.04 | 79.24 ± 0.02 |
| F7 | 1:3 | 25 | 21.27 ± 0.01 | 85.08 ± 0.02 | 38.37 ± 0.23 |
| F8 | 1:3 | 25 | 21.83 ± 0.02 | 87.32 ± 0.01 | 40.52 ± 0.12 |
| F9 | 1:3 | 25 | 22.87 ± 0.01 | 91.48 ± 0.01 | 45.31 ± 0.18 |
| F10 | 1:3 | 25 | 23.13 ± 0.01 | 92.52 ± 0.03 | 47.84 ± 0.16 |
a
Standard deviation mean “n” = 3.