Table 5.
Effect of drug–polymer ratio.
| Batches | Drug:polymer ratio | Production yield (%) ± SDa | Drug content (%) ± SDa | Encapsulation efficiency (%) ± SDa | % CDR ± SDa | Flux (mg/cm2 h) |
|---|---|---|---|---|---|---|
| F1 | 1:1 | 24.55 ± 0.26 | 47.78 ± 0.01 | 95.56 ± 0.02 | 84.18 ± 0.01 | 0.3181 |
| F2 | 1:2 | 38.8 ± 0.23 | 31.04 ± 0.03 | 93.12 ± 0.02 | 75.88 ± 0.03 | 0.2968 |
| F3 | 1:3 | 42.6 ± 0.42 | 22.49 ± 0.01 | 89.96 ± 0.06 | 59.12 ± 0.02 | 0.2207 |
| F4 | 1:4 | 59.2 ± 0.01 | 16.36 ± 0.17 | 81.8 ± 0.20 | 50.27 ± 0.05 | 0.1999 |
| F5 | 1:5 | 71.13 ± 0.08 | 12.61 ± 0.02 | 75.82 ± 0.03 | 43.66 ± 0.01 | 0.1742 |
| F6 | 1:6 | 79.24 ± 0.02 | 9.75 ± 0.01 | 68.22 ± 0.04 | 40.69 ± 0.01 | 0.1621 |
a
Standard deviation mean “n” = 3.