Table 5. Influence of the nuclear factor erythroid 2-related factor (Nrf2) (rs6726395) on the results of prenatal exposure to both PM2.5 and ETS.
| Nrf2 GG | Nrf2 GA+AA | Nrf2 GG | Nrf2 GA+AA | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LRTIs | LRTIs | URTIs | URTIs | |||||||||
| No (n=98) | Yes (n=22) | No (n=153) | Yes (n=27) | No (n=36) | Yes (n=87) | No (n=37) | Yes (n=150) | |||||
| n | n | aOR* (95% CI) | n | n | aOR* (95% CI) | n | n | aOR* (95% CI) | n | n | aOR* (95% CI) | |
| PM2.5 (Low) | 31 | 2 | 1.00 | 32 | 3 | 1.00 | 9 | 24 | 1.00 | 7 | 29 | 1.00 |
| ETS (No) | ||||||||||||
| PM2.5 (Low) | 26 | 10 | 9.66 | 57 | 9 | 1.19 | 9 | 27 | 1.20 | 15 | 54 | 1.09 |
| ETS (Yes) | (0.99, 94.03) | (0.27, 5.18) | (0.36, 3.94) | (0.34, 3.53) | ||||||||
| PM2.5 (High) | 20 | 2 | 4.27 | 21 | 4 | 1.19 | 9 | 15 | 0.66 | 4 | 22 | 1.65 |
| ETS (No) | (0.31, 58.04) | (0.19, 7.31) | (0.19, 2.29) | (0.36, 7.52) | ||||||||
| PM2.5 (High) | 21 | 8 | 23.69 | 43 | 11 | 2.82 | 9 | 21 | 0.81 | 11 | 45 | 1.75 |
| ETS (Yes) | (2.13, 263.07) | (0.65, 12.31) | (0.23, 2.94) | (0.48, 6.42) | ||||||||
*Odds ratios were adjusted for maternal age, maternal body mass index, maternal educational state, infant sex, gestational age, delivery mode, and family history of allergy.
aOR, adjusted odds ratio; CI, confidence interval; ETS, environmental tobacco smoke; PM2.5, fine particulate matter; Nrf2, nuclear factor erythroid 2-related factor; LRTIs, lower respiratory tract infections; URTIs, upper respiratory tract infections.