Table 2. Net % inhibition of histamine release (IHR) by prepared human basophils from non-atopic individual sensitized with atopic serum in the presence of purified camel IgG isotypes.
| Camel IgG isotype | Source of camel IgG isotype | |||
|---|---|---|---|---|
| Preimmune sera | Postimmune sera | |||
| HR (ng/mL) | % Inhibition of HR* | HR (ng/mL) | % Inhibition of HR | |
| IgG1 | 9.78 | 4.99 | 5.48 | 60.05 |
| IgG2 | 9.86 | 3.96 | 2.83 | 93.98 |
| IgG3 | 9.90 | 3.45 | 2.59 | 97.05 |
Induced HR in the absence of camel IgG: 10.17 ng/mL; Spontaneous HR: 2.36 ng/mL. Where A1 represents induced HR in absence of camel IgG, A2 represents induced HR in the presence of camel IgG, Sp, spontaneous HR.
*Net % inhibition of HR was calculated as per the formula: ([A1-Sp]-[A2-Sp])/(A1-Sp).