Table 1.
Characteristic | Total (N = 575) |
Observation (surgery alone; n = 293) |
ACT (n = 282) |
P* | |||
---|---|---|---|---|---|---|---|
No. | % | No. | % | No. | % | ||
Sex | .18 | ||||||
Male | 365 | 63 | 179 | 61 | 186 | 66 | |
Female | 210 | 37 | 114 | 39 | 96 | 34 | |
Age, years | .56 | ||||||
< 55 | 200 | 35 | 101 | 34 | 99 | 35 | |
55 to 64 | 216 | 38 | 119 | 41 | 97 | 34 | |
≥ 65 | 159 | 28 | 73 | 25 | 86 | 31 | |
Stage | .87 | ||||||
I | 310 | 54 | 152 | 52 | 158 | 56 | |
II | 179 | 31 | 95 | 32 | 84 | 30 | |
III | 86 | 15 | 46 | 16 | 40 | 14 | |
N stage | .78 | ||||||
N0 | 325 | 57 | 162 | 55 | 163 | 58 | |
N1 | 174 | 30 | 89 | 30 | 85 | 30 | |
N2 | 76 | 13 | 42 | 14 | 34 | 12 | |
T stage | .52 | ||||||
1 | 88 | 15 | 42 | 14 | 46 | 16 | |
2 | 446 | 78 | 230 | 79 | 216 | 77 | |
3 to 4 | 41 | 7 | 21 | 7 | 20 | 7 | |
Type of surgery | .08 | ||||||
Pneumonectomy | 99 | 17 | 43 | 15 | 56 | 20 | |
Other | 476 | 83 | 250 | 85 | 226 | 80 | |
WHO PS | .84 | ||||||
0 | 327 | 57 | 162 | 55 | 165 | 59 | |
1 to 2 | 248 | 43 | 131 | 45 | 117 | 41 | |
Adenocarcinoma subtype | .21 | ||||||
Lepidic | 23 | 4 | 13 | 4 | 10 | 4 | |
Acinar | 148 | 26 | 74 | 25 | 74 | 26 | |
Papillary | 99 | 17 | 42 | 14 | 57 | 20 | |
Micropapillary | 39 | 7 | 25 | 9 | 14 | 5 | |
Solid | 266 | 46 | 139 | 47 | 127 | 45 |
Abbreviations: ACT, adjuvant chemotherapy; ATS, American Thoracic Society; ERS, European Respiratory Society; IASLC, International Association for the Study of Lung Cancer; PS, performance status.
χ2 test was calculated from logistic regression model stratified by trial.