Table 4.
Genetic variants of the REN and reduction in blood pressure (valsartan therapy).
| REN C-5312T | SBP (mmHg) | P | DBP (mmHg) | P ∗ | ||
|---|---|---|---|---|---|---|
| Baseline | ARB | Baseline | ARB | |||
| CT/TT | 155.2 ± 15.3 | 135 ± 13.6 | 0.56 | 93.20 ± 15.5 | 83.2 ± 13.6 | 0.04 |
| CC | 140.65 ± 19.03 | 120.5 ± 20.5 | 92.45 ± 15.23 | 80.1 ± 14.6 | ||
Data are means ± SD. Statistical analysis of the difference was performed by independent t-test as appropriate. ∗ P value was calculated for the statistics showing the interactive effect of ARB administration and category in patients on DBP.