[Table/Fig-2]:

Changes in heart rate and mean arterial pressure at various time intervals

Time	Heart rate			Mean arterial pressure
	Group A	Group B	p value	Group A	Group B	p value
Basal	80.13 ± 11.6	81.97± 8.51	0.598 NS	97.1 ± 14.59	94.2 ± 8.93	0.352 NS
After study drug	60.3± 9.46	76.20± 17.37	0.001***	83.7 ± 12.12	73.6 ± 12.36	0.002**
After intubation	75.10± 13.92	99.87± 19.78	0.001***	95.2 ± 16.92	109 ± 20.36	0.006**
1 min	70.03± 12.34	87.17± 17.67	0.001***	87.2 ± 13.19	94.7 ± 16.66	0.060 NS
2 min	67.63± 11.52	83.50± 17.52	0.001***	83.3 ± 11.09	86.7 ± 15.58	0.325 NS
3 min	66.60± 10.93	80.90± 18.09	0.001***	80.3 ± 10.62	83.9 ± 15.21	0.292 NS
4 min	65.97± 10.16	79.47± 16.91	0.001***	77.7 ± 10.73	83.1 ± 14.12	0.099 NS
5 min	65.23± 10.18	76.37± 16.49	0.003**	75.8 ± 11.28	80.6 ± 13.17	0.135 NS
6 min	64.60± 9.59	75.37± 16.21	0.003**	73.9 ± 10.45	79.1 ± 12.49	0.082 NS
7 min	63.83± 8.86	73.93± 16.02	0.004**	73.0 ± 10.55	77.1 ± 11.24	0.147 NS
8 min	63.50± 8.82	72.47± 15.44	0.008**	71.4 ± 11.58	74.3 ± 10.04	0.316 NS
9 min	62.87± 9.51	71.17± 15.53	0.015*	70.4 ± 10..80	73.5 ± 9.90	0.251 NS
10 min	62.40± 9.22	70.10± 15.51	0.023*	69.4 ± 10.84	72.2 ± 9.53	0.292 NS

*Significant, ** Highly significant, *** Very highly significant