Figure 6.

Plateau [Ca²⁺]_i responses to ACh correlate with [Ca²⁺]_i responses to depolarization

A, scatter plot illustrating magnitude of ∆F ₃₄₀/F ₃₈₀ during negative current injections of −1, −3 and −5 nA during the plateau ∆F ₃₄₀/F ₃₈₀ response to 100 nm ACh (Y‐axis) versus the plateau ∆F ₃₄₀/F ₃₈₀ response (from resting baseline) to 100 nm ACh (X‐axis). Note lack of correlation (R ² < 0.035). B, as in A during positive current injections of +1, +3 and +5 nA. Note negative correlations between the decreased [Ca²⁺]_i during depolarization and the plateau [Ca²⁺]_i response to ACh (R ² > 0.55). Individual data points correspond to summary data in Fig. 5 B.