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. 2015 Sep 14;593(20):4631–4648. doi: 10.1113/JP270487

Table 4.

Muscle metabolism during 10 s sprints performed after a standardized warm‐up (Control), and at the end of an incremental exercise to exhaustion in normoxia (PIO2 = ∼143 mmHg) and severe hypoxia (PIO2 = ∼73 mmHg), following recovery periods of either 10 or 60 s with vascular occlusion (n = 11)

Control Nx 10 s Nx 60 s Hyp 10s Hyp 60s Main FIO2 (P) Main Occ (P) Interaction FIO2 × Occ (P)
Legs V˙O2 (l min−1) 0.542 ± 0.229a 1.562 ± 0.325 0.937 ± 0.313b 1.958 ± 0.488b,c 0.775 ± 0.287b,d 0.09 0.001 0.003
Legs V˙O2 (ml kg−1 min−1) 75.9 ± 36.7a 216.5 ± 56.0 129.8 ± 46.4b 272.7 ± 82.3b,c 108.9 ± 45.5b,d 0.09 0.001 0.003
ATP turnover V˙O2 (mmol kg−1 s−1) 0.106 ± 0.045a 0.306 ± 0.064 0.184 ± 0.061b 0.384 ± 0.096b,c 0.152 ± 0.056b,d 0.09 0.001 0.003
ATP turnover total O2 (mmol kg−1 s−1) 0.205 ± 0.058a 0.434 ± 0.091 0.293 ± 0.077b 0.526 ± 0.135b,c 0.258 ± 0.076b,d 0.09 0.001 0.002
Total ATP demand (mmol kg−1 s−1) 1.184 ± 0.250a 0.625 ± 0.123 0.785 ± 0.173b 0.698 ± 0.187 0.792 ± 0.220b 0.294 0.003 0.251
Anaerobic ATP turnover (mmol kg−1 s−1) 0.980 ± 0.213a 0.191 ± 0.058 0.492 ± 0.164b 0.172 ± 0.161c 0.534 ± 0.219b,d 0.779 0.001 0.358
%Anaerobic 82.7 ± 3.2a 30.4 ± 6.9 61.7 ± 10.8 22.3 ± 16.8 65.8 ± 11.3 0.530 0.001 0.051
ATP turnover occlusion (mmol kg−1 s−1) 0.176 ± 0.142 0.185 ± 0.234
Anaerobic reserve (mmol kg−1) 17.3 ± 9.8 17.8 ± 16.2
a

P < 0.05 compared with the other conditions;

b P < 0.05 compared with Nx 10 s;

c P < 0.05 compared with Nx 60 s;

d P < 0.05 compared with Hyp 10 s;

RM ANOVA (2 × 2) Main FIO2: main oxygenation effect due to the conditions in which the incremental exercise test was performed (Nx: normoxia; Hyp: hypoxia); RM ANOVA (2 × 2) Main Occ: main occlusion effect due to the duration of the occlusion (10 s vs. 60 s); assuming a wet‐to‐dry weight muscle ratio of 4.5:1 (Putman et al. 1998); ATP turnover total O2 = aerobic ATP turnover from leg V˙O2 + ATP turnover from O2 stores; Anaerobic ATP turnover: energy supplied by phosphagens and glycolysis (the energy supplied by lactate oxidation is computed as aerobic ATP turnover).