Table 1.

Body Weights (g) of Fischer 344 Rats Before OVX Procedure and After Final Treatment

	Pre-op Weight (g)		Final Weight (g)
Treatment	Vehicle	E2	Vehicle	E2
1 week	285.4 ± 4.8	278.5 ± 6.8	280.8 ± 4.7	274.0 ± 6.8
4 weeks	268.5 ± 5.4	273.8 ± 9	277.8 ± 3.9	282.0 ± 8.9
8 weeks	272.0 ± 3.6	272.8 ± 5.8	298.2 ± 7.3	301.2 ± 4.8
12 weeks	280.5 ± 7.5	285.9 ± 6.7	312.7 ± 6.5	318.3 ± 4.2

There were no statistically significant differences in body weight between treatment groups.