Table 1.
Cre, Chow Diet | FaChOX, Chow Diet | Cre, Western Diet | FaChOX, Western Diet | |
---|---|---|---|---|
BAT weight, g | 0.113 ± 0.006 | 0.089 ± 0.006 | 0.242 ± 0.017a | 0.182 ± 0.014a,b |
Epididymal WAT weight, g | 0.85 ± 0.08 | 0.59 ± 0.06 | 2.60 ± 0.12a | 2.21 ± 0.17a,b |
Liver weight, g | 1.51 ± 0.04 | 1.41 ± 0.03 | 2.46 ± 0.15a | 1.85 ± 0.11a,b |
Spleen weight, g | 0.080 ± 0.003 | 0.075 ± 0.002 | 0.099 ± 0.002a | 0.092 ± 0.003a |
Fasting cholesterol, mg/dL | 140 ± 11 | 134 ± 8 | 222 ± 9a | 194 ± 10a |
Fasting triglycerides, mg/dL | 58 ± 4 | 56 ± 2 | 49 ± 2 | 48 ± 1 |
Tissues (n = 15–17 per group) were dissected from ad libitum-fed mice, and plasma lipids (n = 9–14 per group) were measured in 6-hour-fasted mice at the end of the study. Data shown are mean ± SEM.
P < .01 compared with chow diet mice of the same genotype.
P < .05 compared with Cre control.