Table 3.
Population attributable fraction (PAF) and estimated numbers of cancers diagnosed in Australia in 2010 attributable to different infectious agents
| Estimated number of cancer cases by infectious agent | Total | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Cancer site (ICD-10 code) | HPV | H pylori | EBV | HBV | HCV | HIV | KSHV | No. of cancers | PAF |
| Males | |||||||||
| Oral cavity (C02-C04) | 53 | 53 | 6.8 | ||||||
| Oropharynx (C01, C05, C09, C10) | 237 | 237 | 39.7 | ||||||
| Nasopharynx (C11) | 74 | 74 | 87.0 | ||||||
| Stomach (C16) | 431 | 431 | 32.9 | ||||||
| Anus (C21) | 108 | ** | 108 | 74.9 | |||||
| Liver (C22) | 162 | 190 | 352 | 34.4 | |||||
| Kaposi Sarcoma (C46) | ** | 58 | 58 | 100.0 | |||||
| Penis (C60) | 38 | 38 | 45.4 | ||||||
| Hodgkin's lymphoma (C81) | 110 | ** | 110 | 31.5 | |||||
| Non-Hodgkin's lymphoma (C82-C85, C96) | 56 | 9 | 20 | 16 | 101 | 3.9 | |||
| Total | 436 | 487 | 193 | 162 | 210 | 16 | 58 | 1562 | |
| % of all cancersa | 0.7% | 0.7% | 0.3% | 0.2% | 0.3% | 0.02% | 0.1% | 2.4% | |
| Females | |||||||||
| Oral cavity (C02-C04) | 24 | 24 | 6.8 | ||||||
| Oropharynx (C01, C05, C09, C10) | 67 | 67 | 39.8 | ||||||
| Nasopharynx (C11) | 33 | 33 | 87.0 | ||||||
| Stomach (C16) | 263 | 263 | 38.5 | ||||||
| Anus (C21) | 180 | ** | 180 | 90.8 | |||||
| Liver (C22) | 60 | 71 | 131 | 34.4 | |||||
| Kaposi Sarcoma (C46) | ** | 22 | 22 | 100.0 | |||||
| Vulva (C51) | 120 | 120 | 40.4 | ||||||
| Vagina (C52) | 61 | 61 | 69.9 | ||||||
| Uterine Cervix (C53) | 818 | ** | 818 | 100.0 | |||||
| Hodgkin's lymphoma (C81) | 78 | 78 | 31.5 | ||||||
| Non-Hodgkin's lymphoma (C82-C85, C96) | 43 | 3 | 15 | 1 | 62 | 3.2 | |||
| Total | 1270 | 306 | 114 | 60 | 86 | 1 | 22 | 1859 | |
| % of all cancersa | 2.5% | 0.6% | 0.2% | 0.1% | 0.2% | 0.0% | 0.04% | 3.7% | |
| Persons | |||||||||
| Oral cavity (C02-C04) | 77 | 77 | 6.8 | ||||||
| Oropharynx (C01, C05, C09, C10) | 304 | 304 | 39.8 | ||||||
| Nasopharynx (C11) | 107 | 107 | 87.0 | ||||||
| Stomach (C16) | 694 | 694 | 34.8 | ||||||
| Anus (C21) | 288 | 288 | 84.1 | ||||||
| Liver (C22) | 222 | 261 | 483 | 34.4 | |||||
| Kaposi Sarcoma (C46) | 80 | 80 | 100.0 | ||||||
| Vulva (C51) | 120 | 120 | 40.4 | ||||||
| Vagina (C52) | 61 | 61 | 69.9 | ||||||
| Uterine Cervix (C53) | 818 | 818 | 100.0 | ||||||
| Penis (C60) | 38 | 38 | 45.4 | ||||||
| Hodgkin's lymphoma (C81) | 188 | 188 | 32.9 | ||||||
| Non-Hodgkin's lymphoma (C82-C85, C96) | 99 | 12 | 35 | 17 | 163 | 3.6 | |||
| Total | 1706 | 793 | 307 | 222 | 296 | 17 | 80 | 3421 | |
| % of all cancersa | 1.5% | 0.7% | 0.3% | 0.2% | 0.3% | 0.01% | 0.1% | 2.9% | |
Abbreviations: HPV = human papillomavirus; H pylori = Helicobacter pylori; EBV = Epstein-Barr virus; HBV = Hepatitis B virus; HCV = Hepatitis C virus; HIV = Human immunodeficiency virus; KSHV = Kaposi's sarcoma herpes virus; PAF = population attributable fraction (expressed as a percentage)
a: % of all cancers diagnosed in 2010 excluding basal cell carcinoma and squamous cell carcinoma of the skin
** Numbers not calculated separately as HIV is not necessary or sufficient