Table 2.

Summary of similarities and differences between HMC and TC

S.No.	Features	TC	HMC
1.	Somatic cell nuclear transfer	✓	✓
2.	Synchronization of donor cell	✓	✓
3.	High no. of attempts	✓	✓
4.	Problems associated with nuclear reprogramming and reproducibility of experiments	✓	✓
5.	True clone	×	×
6.	Micromanipulator-free	×	✓
7.	Zona- free	×	✓
8.	Problems associated with zona pellucida removal	×	✓
9.	Number of cytoplast required	Lower	Higher
10.	Costs	Higher	Lower than TC