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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Leukemia. 2015 Jul 3;30(1):163–172. doi: 10.1038/leu.2015.174

Figure 6. IL-10 modulation of Foxp3 expression in Tregs from WT and EμTCL1-Tg mice.

Figure 6

(A) CD4+CD25+CD39+ regulatory T cells isolated from WT and EμTCL1-Tg mice were cultured for 12-hr +/− IL-10 with or without anti-BAFF blocking antibody and assessed for intracellular Foxp3 expression by flow cytometry. (B) MFI levels of intracellular Foxp3 in Tregs from WT and EμTCL1-Tg mice cultured for 12-hr +/−IL-10 with or without anti-BAFF blocking antibody. (C) CD4+CD25+CD39+ regulatory T cells isolated from WT and EμTCL1-Tg mice were cultured for 12-hr +/−BAFF and anti-IL-10 blocking antibody and assessed for intracellular Foxp3 expression by flow cytometry. (B) MFI levels of intracellular Foxp3 in Tregs from WT and EμTCL1-Tg mice cultured for 12-hr +/− BAFF and anti-IL-10 blocking antibody. In B and D, horizontal bars indicate the mean. In A-D, data are representative of at least two independent experiments.