Table 1.
Baseline characteristics
| Body Mass Index | |||||
|---|---|---|---|---|---|
| Total | Normal or underweight | Overweight | Obese | p-value* | |
| ≤ 22.9 kg/m2 | 23–24.9 kg/m2 | ≥ 25 kg/m2 | |||
| N (%) | N (%) | N (%) | N (%) | ||
| Total | 522 (100) | 184 (35.2) | 152 (29.1) | 186 (35.6) | |
| Age | 0.028 | ||||
| < 65 years | 366 (70.1) | 138 (75.0) | 108 (71.1) | 120 (64.5) | 0.42 |
| ≥ 65 years | 156 (29.9) | 46 (25.0) | 44 (28.9) | 66 (35.5) | 0.028 |
| Sex | 0.094 | ||||
| Male | 312 (59.8) | 99 (53.8) | 97 (63.8) | 116 (62.4) | 0.064 |
| Female | 210 (40.2) | 85 (46.2) | 55 (36.2) | 70 (37.6) | 0.095 |
| Location | 0.56 | ||||
| Proximal | 181 (34.7) | 63 (34.2) | 49 (32.2) | 69 (37.1) | 0.70 |
| Distal | 341 (65.3) | 121 (65.8) | 103 (67.8) | 117 (62.9) | 0.57 |
| T stage | 0.17 | ||||
| T1 - 3 | 446 (85.4) | 149 (81.0) | 137 (90.1) | 160 (86.0) | 0.019 |
| T4 | 76 (14.6) | 35 (19.0) | 15 (9.9) | 26 (14.0) | 0.19 |
| N stage | 0.96 | ||||
| N0 - 1 | 380 (72.8) | 133 (72.3) | 113 (74.3) | 134 (72.0) | 0.67 |
| N2 | 142 (27.2) | 51 (27.7) | 39 (25.7) | 52 (28.0) | 0.96 |
| Tumor stage | 0.073 | ||||
| II, high-risk | 78 (14.9) | 37 (20.1) | 16 (10.5) | 25 (13.4) | 0.016 |
| III | 444 (85.1) | 147 (79.9) | 136 (89.5) | 161 (86.6) | 0.086 |
| Histology | 0.15 | ||||
| MAC | 27 (5.2) | 12 (6.5) | 9 (5.9) | 6 (3.2) | 0.82 |
| Non-MAC | 495 (94.8) | 172 (93.5) | 143 (94.1) | 180 (96.8) | 0.14 |
| Microsatellite status (N = 517) | 0.062 | ||||
| MSS/MSI-L | 480 (92.8) | 163 (90.1) | 142 (93.4) | 175 (95.1) | 0.27 |
| MSI-H | 37 (7.2) | 18 (9.9) | 10 (6.6) | 9 (4.9) | 0.065 |
Abbreviations: MAC mucinous adenocarcinoma, MSS microsatellite stable, MSI-L microsatellite instability-low, MSI-H microsatellite instability-high
*Upper row: linear-by-linear association test, middle row: Χ2 test of normal or underweight vs. overweight, lower row: Χ2 test of normal or underweight vs. obese