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. 2015 Sep 14;125(10):3928–3940. doi: 10.1172/JCI79271

Figure 6. 4-MU treatment promotes nondestructive insulitis.

Figure 6

(A–D) Insulin staining of representative pancreatic tissue sections from DORmO and BALB/c mice fed either 4-MU or control chow. (E) Average insulin+ area of islets for these mice. 25 islets were visualized per mouse, and staining and data are for 6 mice per condition. (F and G) Representative images of insulin staining of pancreatic islets from 15-week-old DORmO mice treated with 4-MU for 7 weeks. Original magnification, ×40. Data represent mean ± SEM; *P < 0.05 vs. respective control by unpaired t test.