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. 2015 Sep 8;125(10):3809–3818. doi: 10.1172/JCI77095

Figure 2. Trib1_LSKO mice have increased plasma TC, HDL and non-HDL cholesterol, and plasma TGs.

Figure 2

(A) Plasma TC, non-HDL cholesterol, and TG in male Trib1_fl/fl or Trib1_LSKO mice (n = 10) 4 weeks after injection. Plasma samples were collected after mice were fasted for 4 hours. (B) Plasma TC, non-HDL cholesterol, and TG after 4-hour fast in female Trib1_fl/fl and Trib1_LSKO mice (n = 10) 4 weeks after injection. (C) Plasma TC in male Trib1_fl/fl and Trib1_LSKO mice (n = 5) out to 20 weeks after injection. (D) Change from baseline for non-HDL cholesterol in the same male Trib1_fl/fl and Trib1_LSKO mice from C. All plasma levels were measured by Cobas-Mira autoanalyzer with commercially available reagents. Significance was determined in all panels by Student’s t test (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001).