Table 2.
Neonatal baseline characteristics.
| Buprenorphine/naloxone | Methadone | p-value | |
|---|---|---|---|
| Number of infants | 58 | 92 | |
| Males, n (%) | 30 (52) | 55 (60) | NS |
| GA (weeks)a | 38 ± 2 | 38 ± 2 | NS |
| ≤36 w, n (%) | 10 (17) | 22 (24) | NS |
| 37–41 w, n (%) | 48 (83) | 70 (76) | NS |
| Birth weight (g)a | 2905 ± 567 | 2904 ± 522 | NS |
| Length (cm)a | 49 ± 4 | 49 ± 4 | NS |
| Head circumference (cm)a | 33 ± 2 | 33 ± 3 | NS |
| Apgar score <5 at 1 min, n (%) | 2 (3) | 2 (2) | NS |
| Apgar < 5 at 5 min, n (%) | 0 (0) | 1 (1) | NS |
| NICU admissions, n (%) | 15 (25) | 18 (20) | NS |
| Respiratory distress | 10 (17) | 13 (14) | NS |
| Prematurity | 3 (5) | 4 (4) | NS |
| Miscellaneous | 2 (3) | 1 (1) | NS |
| Hospital stay (days)a | 9 ± 6 | 10 ± 8 | NS |
| Weight at discharge (g)a | 2912 ± 569 | 2884 ± 494 | NS |
| Initiated breastfeeding, n (%) | 10 (17) | 41 (45) | 0.001 |
GA: Gestational age; NICU: neonatal intensive care unit; SD: standard deviation.
a
Mean ± SD.