Table 2.
Estimated Global Burden of Shiga Toxin–Producing Escherichia coli, Circa 2012, by World Health Organization (WHO) Sub-regions
| WHO Sub-region | 2005 WHO Sub-region population | Estimated burden (mean value)a
|
||||
|---|---|---|---|---|---|---|
| No. cases | Incidence per 100,000 person-years | No. cases hemolytic uremic syndrome | No. cases end-stage renal disease | No. deaths | ||
| AFR D | 353,412,879 | 4800 | 1.4 | 5 | 0 | 0 |
| AFR E | 402,012,097 | 5400 | 1.4 | 5 | 0 | 0 |
| AMR A | 343,376,860 | 321,000 | 93.5 | 1000 | 70 | 60 |
| AMR B | 464,046,150 | 126,200 | 27.2 | 400 | 30 | 20 |
| AMR D | 76,985,668 | 71,900 | 93.5 | 80 | 5 | 5 |
| EMR B | 148,336,863 | 226,300 | 152.6 | 60 | 5 | 5 |
| EMR D | 381,484,794 | 582,000 | 152.6 | 160 | 10 | 15 |
| EUR A | 423,910,793 | 199,500 | 47.1 | 630 | 40 | 35 |
| EUR B | 224,521,283 | 6000 | 2.7 | 20 | < 5 | < 5 |
| EUR C | 236,910,762 | 6000 | 2.5 | 20 | < 5 | < 5 |
| SEAR B | 308,186,718 | 204,300 | 66.3 | 220 | 15 | 15 |
| SEAR D | 1,388,360,385 | 920,200 | 66.3 | 1000 | 70 | 60 |
| WPR A | 157,005,359 | 69,900 | 44.5 | 220 | 15 | 10 |
| WPR B | 1,593,805,917 | 56,100 | 3.5 | 60 | 5 | 5 |
| Global TOTALS b | 6,502,356,528 | 2,801,000 | 43.1 | 3890 | 270 | 230 |
a
Values were rounded to the nearest 5; values between 1 and 5 inclusive are represented as “ < 5.” Results reported here are mean values of the distributions generated from the simulation model, and as such will be different than the most likely values reported in Table 1.
b
Numbers may not add up due to rounding.