Table 1.
Mean values of contractions (±S.E., g) of Ascaris suum muscle flaps caused by increasing concentrations of acetylcholine and the inhibitory effect of carvacrol (100 and 300 μM) on these contractions
n=8 | 1 μM ACh | 3 μM ACh | 10 μM ACh | 30 μM ACh | 100 μM ACh |
---|---|---|---|---|---|
Control | 0.54±0.08 | 1.11±0.15 | 1.40±0.17 | 2.09±0.25 | 2.35±0.21 |
Carvacrol 100 μM | 0.26±0.04* | 0.81±0.11** | 1.16±0.16 | 1.84±0.21 | 2.03±0.24** |
Carvacrol 300 μM | 0.10±0.01** | 0.26±0.07*** | 0.35±0.10*** | 0.96±0.17*** | 1.26±0.19*** |
Wash | 0.17±0.01 | 0.62±0.13 | 0.99±0.13 | 1.84±0.21 | 2.26±0.23 |
*p=0.0248 | **p=0.0076 | ***p=0.0002 | ***p<0.0001 | **p=0.0092 | |
**p=0.0023 | ***p=0.0002 | ***p<0.0001 |
Statistically significant difference compared to control