Table 2. Odds ratio for cardiovascular disease by depression status and severity of depression and anxious distress (n = 10,341).
| Cardiovascular diseases | Ischemic/hypertensive heart disease | Stroke | |||||||
|---|---|---|---|---|---|---|---|---|---|
| N = 514 | N = 364 | N = 228 | |||||||
| Model 1 1 | Model 2 2 | Model 3 3 | Model 1 1 | Model 2 2 | Model 3 3 | Model 1 1 | Model 2 2 | Model 3 3 | |
| OR (95%) | OR (95%) | OR (95%) | OR (95%) | OR (95%) | OR (95%) | OR (95%) | OR (95%) | OR (95%) | |
| Depression status (MDI) | |||||||||
| No | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| Yes | 1.9(1.4,2.5) | 1.7(1.2,2.3) | 1.5(1.1,2.1) | 1.8(1.3,2.5) | 1.6(1.1,2.3) | 1.5(1.0,2.1) | 2.0(1.4,3.0) | 1.8(1.2,2.7) | 1.7(1.1,2.6) |
| Level of depression (MDI) | |||||||||
| No depression | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| Mild depression | 1.5(0.98,2.5) | 1.4 (0.8,2.3) | 1.3 (0.8,2.2) | 1.9 (1.1,3.3) | 1.8 (1.0,3.1) | 1.7 (1.0,3.0) | 1.7 (0.9,3.3) | 1.6 (0.8,3.1) | 1.5 (0.7,3.0) |
| Moderate depression | 2.6 (1.6,4.2) | 2.3(1.4,3.8) | 2.1(1.3,3.5) | 2.1(1.2,3.8) | 1.8(1.0,3.4) | 1.7(0.9,3.3) | 2.7(1.4,5.1) | 2.4(1.2,4.7) | 2.2(1.1,4.3) |
| Severe depression | 1.7 (1.1,2.7) | 1.5(0.9,2.4) | 1.3(0.9,2.2) | 1.4(0.8,2.5) | 1.2(0.7,2.3) | 1.1(0.6,2.0) | 1.9(1.0,3.5) | 1.6(0.9,3.1) | 1.5(0.8,2.9) |
| Depression (MDI) with/without symptoms of anxious distress | |||||||||
| No depression or anxious distress | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| Depression without anxious distress | 1.6 (0.8,3.0) | 1.6(0.8,3.1) | 1.5(0.7,2.9) | 1.4(0.6,3.2) | 1.6(0.7,3.5) | 1.5(0.6,3.4) | 2.2(1.0,4.8) | 2.2(1.0,5.0) | 2.1(0.9,4.7) |
| Depression with anxious distress | 2.1 (1.5,2.9) | 1.8(1.2,2.5) | 1.6(1.1,2.3) | 2.0(1.4,3.0) | 1.7(1.1,2.6) | 1.6(1.0,2.4) | 2.0(1.3,3.1) | 1.7(1.1,2.7) | 1.6(1.0,2.6) |
| Depression (MDI) with/without levels of anxious distress | |||||||||
| No depression or anxious distress | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| Depression without anxious distress | 1.5 (0.8,3.0) | 1.6(0.8,3.1) | 1.5(0.7,2.9) | 1.4(0.6,3.2) | 1.6(0.7,3.5) | 1.5(0.6,3.4) | 2.2(1.0,4.8) | 2.2(1.0,5.0) | 2.1(0.9,4.7) |
| Depression with mild anxious distress | 2.7 (1.8,4.1) | 2.3(1.5,3.5) | 2.1(1.4,3.3) | 3.0(1.9,4.7) | 2.5(1.5,4.1) | 2.4(1.4,3.9) | 2.7(1.5,4.8) | 2.3(1.3,4.1) | 2.1(1.2,3.8) |
| Depression with moderate/severe anxious distress | 1.6 (1.0,2.5) | 1.3(1.4,2.3) | 1.2(0.7,2.0) | 1.2(0.7,2.3) | 1.1(0.6,2.0) | 0.9(0.5,1.8) | 1.5(0.7,2.8) | 1.2(0.6,2.5) | 1.1(0.6,2.3) |
1Model 1 adjusted for age and gender,
2 Model 2 adjusted for age, gender, SEP, history of IHD, stroke, hypertension and diabetes,
3Model 3 adjusted for age and gender, SEP, history of IHD, stroke, hypertension and, diabetes smoking, physical activity, BMI and hazardous alcohol consumption.