Table 1. Demographics and clinicopathological characteristics of 472 patients with UTUC treated by radical nephroureterectomy.
| Preoperative hydronephrosis | ||||
|---|---|---|---|---|
| All patients | Presence | Absence | P value | |
| Number of patients, no. (%) | 472 (100) | 292 (62) | 180 (38) | |
| Median age, years (range) | 67 (24–95) | 66 (25–90) | 67 (24–95) | |
| Age, no. (%) | 0.016 | |||
| ≦ 67 | 242 (51) | 137 (47) | 105 (58) | |
| > 67 | 230 (49) | 155 (53) | 75 (42) | |
| Gender, no. (%) | 0.969 | |||
| Males | 204 (43) | 126 (43) | 78 (43) | |
| Females | 268 (57) | 166 (57) | 102 (57) | |
| Smoking, no. (%) | 0.323 | |||
| No | 373 (79) | 235 (80) | 138 (71) | |
| Yes | 99 (21) | 57 (20) | 42 (29) | |
| Hematuria, no. (%) | < 0.001 | |||
| No | 73 (15) | 64 (22) | 9 (5) | |
| Yes | 399 (85) | 228 (78) | 171 (95) | |
| Flank pain, no. (%) | 0.002 | |||
| No | 351 (74) | 203 (70) | 148 (82) | |
| Yes | 121 (26) | 89 (30) | 32 (18) | |
| Preoperative eGFR (ml/min/1.73m 2 ) | 0.087 | |||
| ≧ 60 | 156 (33) | 88 (30) | 68 (38) | |
| < 60 | 316 (67) | 204 (70) | 112 (62) | |
| Surgery method, no. (%) | 0.100 | |||
| Laparoscopic | 203 (43) | 117 (40) | 86 (48) | |
| Open | 269 (57) | 175 (60) | 94 (52) | |
| Tumor location, no. (%) | < 0.001 | |||
| Renal pelvis | 189 (40) | 89 (30) | 100 (55) | |
| Ureter | 193 (41) | 145 (50) | 48 (27) | |
| Synchronous | 90 (19) | 58 (20) | 32 (18) | |
| Pathological tumor stage, no (%) | 0.041 | |||
| Tis/a | 60 (13) | 38 (13) | 22 (12) | |
| T1 | 130 (27) | 66 (23) | 64 (36) | |
| T2 | 112 (24) | 73 (25) | 39 (22) | |
| T3 | 142 (30) | 95 (32) | 47 (26) | |
| T4 | 28 (6) | 20 (7) | 8 (4) | |
| Lymph node status, no. (%) | 0.098 | |||
| pN0 | 170 (36) | 96 (33) | 74 (41) | |
| pNX | 261 (55) | 166 (57) | 95 (53) | |
| pN1/2 | 41 (9) | 30 (10) | 11 (6) | |
| Pathological tumor grade, no. (%) | 0.104 | |||
| Low | 112 (24) | 62 (21) | 50 (28) | |
| High | 360 (76) | 230 (79) | 130 (72) | |
| Adjuvant chemotherapy, no. (%) | 0.656 | |||
| No | 385 (82) | 240 (82) | 145 (81) | |
| Yes | 87 (18) | 52 (18) | 35 (19) | |
eGFR estimated glomerular filtration rate.