Skip to main content
. 2015 Oct 15;10(10):e0140638. doi: 10.1371/journal.pone.0140638

Fig 2. Firing properties of PV, SOM, and PYR neurons are not affected by the Nlgn3R451C mutation.

Fig 2

Raw traces of action potentials from (A) PV, (B) SOM, and (C) PYR neurons from WT (top) and Nlgn3R451C (bottom) mice in response to a 125 pA step (represented by square pulse beneath each trace) above firing threshold. Scale bars: 25 mV; 50 ms. No difference is observed between Nlgn3R451C and WT mice in the number of action potentials fired at 0–125 pA steps above firing threshold for PV (D), SOM (E), or PYR (F) neurons (PV: WT = 33, Nlgn3R451C = 38; SOM: WT = 31, Nlgn3R451C = 29; PYR: WT = 48, Nlgn3R451C = 50). Inset: IR-DIC images taken with a 40X objective and 2X magnification of each respective cell type. Scale bar = 25 μm.