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. 2015 Aug 6;7(9):2506–2519. doi: 10.1093/gbe/evv150

Table 3.

Comparison of Transition: Transversion and Nonsynonymous:Synonymous SNP Frequencies in Homozygous (Homosite) versus Heterozygous (Heterosite) Murine SNPs

SNP Category Percent Transition Percent Transversion Nonsynonymous (NS) Coding SNPs Synonymous (S) Coding SNPs NS:S (P Valuea)
Homozygous 77.7 22.3 708 1,245 1:1.76 (1.65E-14)
Heterozygous 66.3 33.7 272 425 1:1.56 (2.64E-11)

Note.—Murine homosites from chromosomes 1–3 with at least four lines exhibiting the minor allele are shown.

aP values represent observed SNP frequencies versus those that would be expected if SNPs formed stochastically (Materials and Methods).