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. 2015 Sep 4;7(9):2692–2704. doi: 10.1093/gbe/evv177

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© The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1.— — Secondary structure comparison of Sec tRNAs and other tRNAs in ε-proteobacteria. (A) Consensus structure of ε-proteobacteria tRNAs (n = 1,502); the variable arm found in minor fraction of tRNAs is shown as skeleton diagram in the inset. (B) Covariance structure of tRNA^Ser(TGA) (n = 38), the standard tRNA family more closely related to tRNA^Sec. (C) Covariance structure of tRNA^Sec (n = 21), characterized by the longer D arm, the extra-long variable arm, and nucleotide positions (indicated by arrows) differing from the consensus. Nucleotide conservation and base pair support from covariance analysis (Weinberg and Breaker 2011) are denoted by colors as shown in the legend.